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LGEWIS (version 1.1)

Tests for Genetic Association/Gene-Environment Interaction in Longitudinal Studies

Description

Functions for genome-wide association studies (GWAS)/gene-environment-wide interaction studies (GEWIS) with longitudinal outcomes and exposures. He et al. (2017) "Set-Based Tests for Gene-Environment Interaction in Longitudinal Studies" and He et al. (2017) "Rare-variant association tests in longitudinal studies, with an application to the Multi-Ethnic Study of Atherosclerosis (MESA)".

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Version

Install

install.packages('LGEWIS')

Monthly Downloads

147

Version

1.1

License

GPL-3

Maintainer

Zihuai He

Last Published

September 1st, 2017

Functions in LGEWIS (1.1)

GEI.prelim

The preliminary data management for GEI (tests for gene-environment interaction)
GEI.test

Test the interaction between an environemental exposure and a region/gene by a generalized score type test.
GA.prelim

The preliminary data management for GA (tests for genetic association)
GA.test

Test the association between an quantitative outcome variable and a region/gene by a generalized score type test.
GEI.SSD.All

Gene-environment interaction tests for multiple regions/genes using SSD format files
GEI.SSD.OneSet_SetIndex

Gene-environment interaction tests for a single region/gene using SSD format files
GA.SSD.All

Genetic association tests for multiple regions/genes using SSD format files
GA.SSD.OneSet_SetIndex

Genetic association tests for a single region/gene using SSD format files
LGEWIS.example

Data example for LGEWIS (tests for genetic association or gene-environment interaction)