LPE (version 1.46.0)

quartile.normalize: Normalization based on quartile range

Description

Does Normalization based on quartile range

Usage

quartile.normalize(x, percent=50)

Arguments

x

x is a matrix or data.frame on which normalization has to be performed.

percent

Percentage for which normalization is needed

Value

Returns the normalized data based on quartile normalization

References

J.K. Lee and M.O.Connell(2003). An S-Plus library for the analysis of differential expression. In The Analysis of Gene Expression Data: Methods and Software. Edited by G. Parmigiani, ES Garrett, RA Irizarry ad SL Zegar. Springer, NewYork. Jain et. al. (2003) Local pooled error test for identifying differentially expressed genes with a small number of replicated microarrays, Bioinformatics, 1945-1951.

Jain et. al. (2005) Rank-invariant resampling based estimation of false discovery rate for analysis of small sample microarray data, BMC Bioinformatics, Vol 6, 187.

See Also

lpe

Examples

  library(LPE)
  # Loading the LPE library

  data(Ley) 
 
 dim(Ley)
 # Gives 12488*7
 # First column is ID.

  subset <- 1:1000
  Ley[subset,2:7] <- quartile.normalize(Ley[subset,2:7],percent=50)