LTFGRS

LTFGRS-package

Implementation of several phenotype-based family genetic risk scores with unified input data and data preparation functions to help facilitate the required data preparation and management. The implemented family genetic risk scores are the extended liability threshold model conditional on family history (LT-FH++) from Pedersen (2022) tools:::Rd_expr_doi("10.1016/j.ajhg.2022.01.009") and Pedersen (2023) <a href="https://www.nature.com/articles/s41467-023-41210-z">https://www.nature.com/articles/s41467-023-41210-z</a>, Pearson-Aitken Family Genetic Risk Scores (PA-FGRS) from Krebs (2024) tools:::Rd_expr_doi("10.1016/j.ajhg.2024.09.009"), and family genetic risk score by Kendler (2021) tools:::Rd_expr_doi("10.1001/jamapsychiatry.2021.0336").

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Implementation of several phenotype-based family genetic risk scores
with unified input data and data preparation functions to help facilitate
the required data preparation and management. The implemented family genetic
risk scores are the extended liability threshold model conditional on family history (LT-FH++)
from Pedersen (2022) <doi:10.1016/j.ajhg.2022.01.009> and Pedersen (2023) <https://www.nature.com/articles/s41467-023-41210-z>,
Pearson-Aitken Family Genetic Risk Scores (PA-FGRS) from Krebs (2024) <doi:10.1016/j.ajhg.2024.09.009>,
and family genetic risk score by Kendler (2021) <doi:10.1001/jamapsychiatry.2021.0336>.

Emil Michael Pedersen

Implementation of Several Phenotype-Based Family Genetic Risk
Scores

Jette Steinbach

Lucas Rasmussen

Morten Dybdahl Krebs

LTFGRS-package function

Maintainer: Emil Michael Pedersen <a href="/link/emp%40ph.au.dk?package=LTFGRS&version=1.0.0" data-mini-rdoc="LTFGRS::emp@ph.au.dk">emp@ph.au.dk</a>
Authors:<ul>
<li>Jette Steinbach <a href="/link/jst%40econ.au.dk?package=LTFGRS&version=1.0.0" data-mini-rdoc="LTFGRS::jst@econ.au.dk">jst@econ.au.dk</a></li>
<li>Morten Dybdahl Krebs <a href="/link/morten.dybdahl.krebs%40regionh.dk?package=LTFGRS&version=1.0.0" data-mini-rdoc="LTFGRS::morten.dybdahl.krebs@regionh.dk">morten.dybdahl.krebs@regionh.dk</a></li>
</ul>Other contributors:<ul>
<li>Lucas Rasmussen <a href="/link/lar.ncrr%40au.dk?package=LTFGRS&version=1.0.0" data-mini-rdoc="LTFGRS::lar.ncrr@au.dk">lar.ncrr@au.dk</a> [contributor]</li>
</ul>

Author

Implementation of several phenotype-based family genetic risk scores with unified input data and data preparation functions to help facilitate the required data preparation and management. The implemented family genetic risk scores are the extended liability threshold model conditional on family history (LT-FH++) from Pedersen (2022) tools:::Rd_expr_doi("10.1016/j.ajhg.2022.01.009") and Pedersen (2023) <a href='https://www.nature.com/articles/s41467-023-41210-z'>https://www.nature.com/articles/s41467-023-41210-z</a>, Pearson-Aitken Family Genetic Risk Scores (PA-FGRS) from Krebs (2024) tools:::Rd_expr_doi("10.1016/j.ajhg.2024.09.009"), and family genetic risk score by Kendler (2021) tools:::Rd_expr_doi("10.1001/jamapsychiatry.2021.0336").

LTFGRS: Implementation of Several Phenotype-Based Family Genetic Risk Scores — LTFGRS-package

Maintainer: Emil Michael Pedersen <a href='mailto:emp@ph.au.dk'>emp@ph.au.dk</a>
Authors:<ul>
<li>Jette Steinbach <a href='mailto:jst@econ.au.dk'>jst@econ.au.dk</a></li>
<li>Morten Dybdahl Krebs <a href='mailto:morten.dybdahl.krebs@regionh.dk'>morten.dybdahl.krebs@regionh.dk</a></li>
</ul>

Other contributors:<ul>
<li>Lucas Rasmussen <a href='mailto:lar.ncrr@au.dk'>lar.ncrr@au.dk</a> [contributor]</li>
</ul>

LTFGRS-package: LTFGRS: Implementation of Several Phenotype-Based Family Genetic Risk Scores

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