This function can attach attributes to family graphs, such as lower and upper thresholds, for each family member. This allows for personalised thresholds and other per-family specific attributes. This function wraps around attach_attributes to ease the process of attaching attributes to family graphs in the standard format.
familywise_attach_attributes(
family_graphs,
fam_attr,
fam_graph_col = "fam_graph",
attached_fam_graph_col = "masked_fam_graph",
fid = "fid",
pid = "pid",
cols_to_attach = c("lower", "upper"),
censor_proband_thrs = TRUE
)tibble with family ids and an updated family graph with attached attributes. If lower and upper thresholds are specified, the input is ready for estimate_liability().
tibble with family ids and family graphs
tibble with attributes for each family member
column name of family graphs in family_graphs. defailts to "fam_graph"
column name of the updated family graphs with attached attributes. defaults to "masked_fam_graph".
column name of family id. Typically contains the name of the proband that a family graph is centred on. defaults to "fid".
personal identifier for each individual in a family. Allows for multiple instances of the same individual across families. Defaults to "pid".
columns to attach to the family graphs from fam_attr, typically lower and upper thresholds. Mixture input also requires K_i and K_pop.
Should proband's upper and lower thresholds be made uninformative? Defaults to TRUE. Used to exclude proband's information for prediction.