plotMethProfile

An rrbs object containing methylation and coverage data as
created using the BiSeq pacakge

rrbs

A GRanges object with each row being a testing region

CpGs

group1

group2

The index within the CpGs object of the region we are
plotting

CpGindex


Plots a smoothed methylation profile for each of the two testing groups.
Within each group, the mean of
methylation level is taken, smoothed and plotted, along with the individual
values.


This package identifies statistically significantly differentially
methylated regions of CpGs. It uses kernel methods (the Maximum Mean
Discrepancy) to measure differences in methylation profiles, and relates
these to inter-replicate changes, whilst accounting for variation in
coverage profiles.

Tom Mayo

Identifies differentially methylated regions across testing groups

plotMethProfile function

Plots a smoothed methylation profile for each of the two testing groups.
Within each group, the mean of
methylation level is taken, smoothed and plotted, along with the individual
values.

plotMethProfile: Plots methylation profiles over a specific region

Description

Usage

Arguments

Value

Examples