MACP (version 0.1.0)

subcellular.mtPPI: Keep Mitochondrial (mt) Proteins

Description

This function removes PPIs occurring between outer mt membrane (OMM) and matrix, between intermembrane space (IMS) and matrix, as well as between any subcellular mt compartment (except OMM) and cytosolic proteins as they deemed to be erroneous

Usage

subcellular.mtPPI(ppi, organism = "mouse")

Value

Filtered PPI netwrok.

Arguments

ppi

Interactions data containing id1-id2-weight triplets.

organism

Organism under study (i.e., mouse or human). Defaults to mouse.

Author

Matineh Rahmatbakhsh,

Details

subcellular.mtPPI

Examples

ppi <-
read.table(system.file("extdata/ppi_input_ClusterONE.txt",
package="MACP"),
quote="\"", comment.char="")
filtered_mtEdges <- subcellular.mtPPI(ppi)