This is a wrapper function for top-scoring pair method.
Usage
TSP(data, varname, B = 50)
Arguments
data
Object of class MetaArray
varname
Character String - name of one column in clinical data matrices to be used as class labels
B
Number of permutations for empirical signifficance
Value
An object of class tsp.res. It is a list
tspTop scoring pair of genes
sigSignificance of top score. It is a list, where p referes to the p-value and nullscores to the top scores achieved in permutations
References
D. Geman, C. d'Avignon, D. Naiman and R. Winslow, "Classifying gene expression profiles from pairwise mRNA comparisons," Statist. Appl. in Genetics and Molecular Biology, 3, 2004.
A.C. Tan, D.Q. Naiman, L. Xu, R.L. Winslow, D. Geman, "Simple decision rules for classifying human cancers from gene expression profiles," Bioinformatics, 21: 3896-3904, 2005.