Learn R Programming

MAMA (version 2.1.0)

VennMapper: Wrapper function for VennMapping

Description

This is a wrapper function for meta-analysis using VennMapping method. It performs all necessary steps and provides all available outputs.

Usage

VennMapper(data, varname, cutoff, ngenes)

Arguments

data
MetaArray object
varname
Character String - name of one column in clinical data matrices to be used as class labels
cutoff
Numeric - cutoff for selection of genes according to their fold-change in log2-scale. e.g. 1 equals to two-fold expression change
ngenes
Numer of genes involved in the analysis

Value

  • An object of class VennMapper.res containing
  • conting.tabA contingency table with numbers of overlapping genes in pairs of the datasets
  • z.scoreA table of z-scores describing the significance of overlap in pairs of the datasets
  • genesA table of gene names that overlap in pairs of the datasets

References

Smid, M., Dorssers, L. C. J. and Jenster, G. 2003, Venn Mapping: clustering of heterologous microarray data based on the number of co-occurring differentially expressed genes, Bioinformatics, vol. 19 no. 16 2003

Examples

Run this code
data(ColonData)
vm<-VennMapper(ColonData, "satelite", 1, 500)

Run the code above in your browser using DataLab