Learn R Programming

MAMS (version 3.0.3)

Designing Multi-Arm Multi-Stage Studies

Description

Designing multi-arm multi-stage studies with (asymptotically) normal endpoints and known variance.

Copy Link

Version

Install

install.packages('MAMS')

Monthly Downloads

577

Version

3.0.3

License

GPL-2

Maintainer

Thomas Jaki

Last Published

August 26th, 2025

Functions in MAMS (3.0.3)

summary.MAMS

Generic summary function for class MAMS.
stepdown.update

Update the stopping boundaries of multi-arm multi-stage study at an interim analysis, allowing for unplanned treatment selection and/or sample-size reassessment.
tite.mams

Function to design multi-arm multi-stage studies with time-to-event endpoints
stepdown.mams

Function to find stopping boundaries for a 2- or 3-stage (step-down) multiple-comparisons-with-control test.
summary.MAMS.stepdown

Generic summary function for class MAMS.stepdown.
print.MAMS.stepdown

Generic print function for class MAMS.stepdown.
.onAttach

.onAttach
ordinal.mams

Function to design multi-arm multi-stage studies with ordinal or binary endpoints
MAMSNews

Shows changes and news
mams

Function to design multi-arm multi-stage studies with normal endpoints
plot.MAMS.stepdown

Plot method for MAMS.stepdown objects
new.bounds

Function to update boundaries based on observed sample sizes
plot.MAMS

Plot method for MAMS objects
print.MAMS

Generic print function for class MAMS.
mams.sim

Simulating multi-arm multi-stage designs