Blood Pressure in Rabbits
Five rabbits were studied on two occasions, after treatment with saline (control) and after treatment with the $5-HT_3$ antagonist MDL 72222. After each treatment ascending doses of phenylbiguanide were injected intravenously at 10 minute intervals and the responses of mean blood pressure measured. The goal was to test whether the cardiogenic chemoreflex elicited by phenylbiguanide depends on the activation of $5-HT_3$ receptors.
J. Ludbrook (1994) Repeated measurements and multiple comparisons in cardiovascular research. Cardiovascular Research 28, 303--311. [The numerical data are not in the paper but were supplied by Professor Ludbrook]
Venables, W. N. and Ripley, B. D. (2002) Modern Applied Statistics with S. Fourth edition. Springer.