Rabbit

0th

Percentile

Blood Pressure in Rabbits

Five rabbits were studied on two occasions, after treatment with saline (control) and after treatment with the \(5-HT_3\) antagonist MDL 72222. After each treatment ascending doses of phenylbiguanide were injected intravenously at 10 minute intervals and the responses of mean blood pressure measured. The goal was to test whether the cardiogenic chemoreflex elicited by phenylbiguanide depends on the activation of \(5-HT_3\) receptors.

Keywords
datasets
Usage
Rabbit
Format

This data frame contains 60 rows and the following variables:

BPchange

change in blood pressure relative to the start of the experiment.

Dose

dose of Phenylbiguanide in micrograms.

Run

label of run ("C1" to "C5", then "M1" to "M5").

Treatment

placebo or the \(5-HT_3\) antagonist MDL 72222.

Animal

label of animal used ("R1" to "R5").

References

Venables, W. N. and Ripley, B. D. (2002) Modern Applied Statistics with S. Fourth edition. Springer.

Aliases
  • Rabbit
Documentation reproduced from package MASS, version 7.3-51.3, License: GPL-2 | GPL-3

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