dnonparam

Used to fit monotonically increasing non-parametric dose-response relationship following
the method of owen2015;textualMBNMAdose)

Fits Bayesian dose-response model-based network meta-analysis (MBNMA)
that incorporate multiple doses within an agent by modelling different dose-response functions, as
described by Mawdsley et al. (2016) <doi:10.1002/psp4.12091>.
By modelling dose-response relationships this can connect networks of evidence that might
otherwise be disconnected, and can improve precision on treatment estimates. Several common
dose-response functions are provided; others may be added by the user. Various characteristics
and assumptions can be flexibly added to the models, such as shared class effects. The consistency
of direct and indirect evidence in the network can be assessed using unrelated mean effects models
and/or by node-splitting at the treatment level.

Hugo Pedder

MBNMAdose

Dose-Response MBNMA Models

Adil Karim

dnonparam function

<dl><dt>direction</dt>
<dd>Can take either <code>"increasing"</code> or <code>"decreasing"</code> to indicate the monotonic direction
of the dose-response relationship</dd></dl>

Arguments

Non-parameteric dose-response functions — dnonparam

<dl>

<dt>direction</dt>
<dd>Can take either <code>"increasing"</code> or <code>"decreasing"</code> to indicate the monotonic direction
of the dose-response relationship</dd>

</dl>

dnonparam: Non-parameteric dose-response functions

Description

Usage

Value

Arguments

References

Examples