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The MBmca package provides data sets and lightweight utilities for nucleic acid melting curve analysis and presentation on microbead surfaces.

Installation

MBmca is available on CRAN, so installation is as simple as:

install.packages("MBmca")

You can install the latest development version of the code using the devtools R package.

# Install devtools, if you haven't already.
install.packages("devtools")

library(devtools)
install_github("MBmca", "michbur")

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Install

install.packages('MBmca')

Monthly Downloads

248

Version

1.1-0

License

GPL (>= 2)

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Maintainer

Andrej-Nikolai Spiess

Last Published

June 11th, 2025

Functions in MBmca (1.1-0)

MultiMelt

Surface melting curve data from direct hybridization experiment of short oligonucleotides.
DualHyb

Surface melting curve data from direct hybridization experiment of short oligonucleotide probes with bimodal melting curve pattern.
DMP

Bimodal melting curve experiment on the surface of microbeads.
MFIerror

Multiple comparison of the temperature dependent variance of the refMFI
MBmca-package

Microbead Surface Nucleic Acid Melting Curve Analysis
diffQ2

Calculation of the melting temperatures (Tm, Tm1D2 and Tm2D2) from the first and the second derivative
diffQ

Calculation of the melting temperature (Tm) from the first derivative
mcaPeaks

Function to estimate the approximate local minima and maxima of melting curve data.
mcaSmoother

Function to pre-process melting curve data.