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MCPModPack (version 0.5)

Simulation-Based Design and Analysis of Dose-Finding Trials

Description

An efficient implementation of the MCPMod (Multiple Comparisons and Modeling) method to support a simulation-based design and analysis of dose-finding trials with normally distributed, binary and count endpoints (Bretz et al. (2005) ).

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Install

install.packages('MCPModPack')

Monthly Downloads

166

Version

0.5

License

GPL-3

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Maintainer

Alex Dmitrienko

Last Published

May 30th, 2023

Functions in MCPModPack (0.5)

normal

Example data set with a continuous endpoint
MCPModPack-package

Design and analysis of dose-finding trials
binary

Example data set with a binary endpoint
count

Example data set with a count endpoint
MCPModSimulation

MCPMod-based simulation of dose-finding trial designs
AnalysisApp

Creation of a Shiny-based interface to perform an MCPMod analysis of a dose-finding trial
SimulationReport

Generation of a Word-based summary of MCPMod simulation results
SimulationApp

Creation of a Shiny-based interface to perform an MCPMod-based simulation of dose-finding trial designs
AnalysisReport

Generation of a Word-based summary of MCPMod analysis results
MCPModAnalysis

MCPMod-based analysis of dose-finding clinical trials with normally distributed, binary and count endpoints