A 1001 by 11 data matrix of a contingency table processed from the FDA Adverse Event Reporting System (FAERS) database. This dataset covers a specific period from Q1 2021 to Q4 2023.
sedative1000A data matrix with 1001 rows and 11 columns.
A 1001 by 11 data matrix of a contingency table from the FDA Adverse Event Reporting System (FAERS) database, covering a specified period from Q1 2021 to Q4 2023.
The 1000 rows correspond to the AEs with the highest overall frequency (row marginals) reported during the period and 1 row for Other AEs. The reported AEs - "Off label use" and "Drug ineffective" have been excluded.
The dataset includes the following 10 columns: Clonazepam, Dexmedetomidine, Diazepam, Diphenhydramine, Doxepin, Lorazepam, Midazolam, Mirtazapine, Nitrazepam, Temazepam, and an Other column.
The marginal totals for each column are as follows: Clonazepam: 110,453, Dexmedetomidine: 4,262, Diazepam: 74,859 Diphenhydramine: 134,65, Doxepin: 11,795, Lorazepam: 101,969 Midazolam: 26,264, Mirtazapine: 54,273, Nitrazepam: 3,473, Temazepam: 20,523, Other: 77,487,518
Also refer to supplementary material of: Ding, Y., Markatou, M., & Ball, R. (2020). An evaluation of statistical approaches to postmarketing surveillance. Statistics in Medicine, 39(7), 845-874
for the data generation process. The quarterly files can be found in https://fis.fda.gov/extensions/FPD-QDE-FAERS/FPD-QDE-FAERS.html.
data(sedative1000)
head(sedative1000)
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