MEDIPS-package:
(MeD)IP-seq data analysis
Description
MEDIPS was developed for analyzing data derived from methylated DNA immunoprecipitation (MeDIP) experiments followed by sequencing (MeDIP-seq).
Nevertheless, several functionalities may be applied to other types of sequencing data (e.g. differential coverage or testing the saturation of ChIP-seq data).
MEDIPS addresses several aspects in the context of MeDIP-seq data analysis including basic data processing, several quality controls, normalization, and identification of differential coverage.
Details
Package: |
MEDIPS |
Type: |
Package |
License: |
GPL (>=2) |
LazyLoad: |
yes |
References
Chavez L, Jozefczuk J, Grimm C, Dietrich J, Timmermann B, Lehrach H, Herwig R, Adjaye J., Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage, Genome Res. 2010 Oct;20(10):1441-50. Epub 2010 Aug 27.