MKomics (version 0.7)

pairwise.mod.t.test: Pairwise Moderated t-Tests

Description

Performs pairwise moderated t-tests (unpaired) based on Bioconductor package limma.

Usage

pairwise.mod.t.test(x, group, adjust.method = "BH", sort.by = "none")

Arguments

x

a (non-empty) numeric matrix of data values.

group

an optional factor representing the groups.

adjust.method

see p.adjust

sort.by

see toptable

Value

A data.frame with the results.

Details

The function uses Bioconductor package limma to compute pairwise moderated t-tests. For more details we refer to ebayes.

References

Ritchie, M.E., Phipson, B., Wu, D., Hu, Y., Law, C.W., Shi, W., and Smyth, G.K. (2015). limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Research 43(7), e47.

See Also

oneway.test, mod.t.test

Examples

# NOT RUN {
set.seed(123)
X <- rbind(matrix(rnorm(5*20), nrow = 5, ncol = 20),
           matrix(rnorm(5*20, mean = 1), nrow = 5, ncol = 20))
gr <- factor(c(rep("A1", 5), rep("B2", 5), rep("C3", 5), rep("D4", 5)))
mod.oneway.test(X, gr)
pairwise.mod.t.test(X, gr)
# }