simdat:
An example dataset
Description
An example dataset with time-to-event outcomes, biomarker values and covariates.
Format
The data contains a list of length 9: time
: Time variable. event
: Event variable. treat
: Treatment variable. cont
: Biomarker data -- continuous values. burden
: Biomarker data -- burden scores of mutations. snps
: Biomarker data -- genotypes of single nucleotide polymorphisms. covar
: covariates. sub.true
: true subgroup size. bio
: combined biomarker data (cbind(cont,burden,snps)
).References
Lin Li, Tobias Guennel, Scott Marshall, Leo Wang-Kit Cheung (2014) A multi-marker molecular signature approach for treatment-specific subgroup identification with survival outcomes. The Pharmacogenomics Journal. http://dx.doi.org/10.1038/tpj.2014.9