simplifiedConsensusTiles

<code>simplifiedConsensusTiles</code> is an R helper function, part of
 the single-cell peak

internal

A statistical framework and analysis tool for open chromatin
analysis designed specifically for single cell ATAC-seq (Assay for
Transposase-Accessible Chromatin) data, after cell type/cluster
identification. These novel modules remove unwanted technical variation,
identify open chromatin, robustly models repeated measures in single cell
data, implement advanced statistical frameworks to model zero-inflation for
differential and co-accessibility analyses, and integrate with existing
databases and modules for downstream analyses to reveal biological insights.
MOCHA provides a statistical foundation for complex downstream analysis to
help advance the potential of single cell ATAC-seq for applied studies.
Methods for zero-inflated statistics are as described in:
Ghazanfar, S., Lin, Y., Su, X. et al. (2020) <doi:10.1038/s41592-020-0885-x>.
Pimentel, Ronald Silva, "Kendall's Tau and Spearman's Rho for Zero-Inflated
Data" (2009) <https://scholarworks.wmich.edu/dissertations/721/>.

Imran McGrath

MOCHA

Modeling for Single-Cell Open Chromatin Analysis

Samir Rachid Zaim

Mark-Phillip Pebworth

Lauren Okada

Xiaojun Li

simplifiedConsensusTiles function

<dl><dt>ref</dt>
<dd>ref a list of data on one specific cell type, sampleData, threshold, groupColumn, and verbose flag.</dd></dl>

Arguments

simplifiedConsensusTiles — simplifiedConsensusTiles

<dl>

<dt>ref</dt>
<dd>ref a list of data on one specific cell type, sampleData, threshold, groupColumn, and verbose flag.</dd>

</dl>

simplifiedConsensusTiles: `simplifiedConsensusTiles`

Description

Usage

Arguments