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MVR (version 1.20.0)

Mean-Variance Regularization

Description

MVR is a non-parametric method for joint adaptive mean-variance regularization and variance stabilization of high-dimensional data. It is suited for handling difficult problems posed by high-dimensional multivariate datasets (p >> n paradigm), among which are that the variance is often a function of the mean, variable-specific estimators of variances are not reliable, and tests statistics have low powers due to a lack of degrees of freedom. Key features include: (i) Normalization and/or variance stabilization of the data, (ii) Computation of mean-variance-regularized t-statistics (F-statistics to follow), (iii) Generation of diverse diagnostic plots, (iv) Computationally efficient implementation using C/C++ interfacing and an option for parallel computing to enjoy a faster and easier experience in the R environment.

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Version

Install

install.packages('MVR')

Monthly Downloads

232

Version

1.20.0

License

GPL (>= 3) | file LICENSE

Maintainer

PhD

Last Published

November 13th, 2013

Functions in MVR (1.20.0)

pooled.mean

Pooled Group Sample Mean Subroutine
mvrt.test

Function for Computing Mean-Variance Regularized T-test Statistic and Its Significance
cluster.diagnostic

Function for Plotting Summary Cluster Diagnostic Plots
withinsumsq

Within-Cluster Sum of Squares Distances Subroutine
normalization.diagnostic

Function for Plotting Summary Normalization Diagnostic Plots
stabilization.diagnostic

Function for Plotting Summary Variance Stabilization Diagnostic Plots
is.empty

Checks if Object is Empty
pooled.sd

Pooled Group Sample Standard Deviation Subroutine
Real

Real Proteomics Dataset
target.diagnostic

Function for Plotting Summary Target Moments Diagnostic Plots
km.clustering

Wrapper Subroutine Around C Subroutine for 'K-means' Clustering Algorithm
mvr

Function for Mean-Variance Regularization and Variance Stabilization
Synthetic

Multi-Groups Synthetic Dataset
MVR-package

Mean-Variance Regularization Package
MVR.news

Function to Display the NEWS File
sim.dis

Similarity Statistic Subroutine
mvrt

Mean-Variance Regularized t-Test Statistic Subroutine
MeanVarReg

Mean-Variance Regularization Core Subroutine
merging.cluster

Variable-Cluster Configuration Merging Subroutine
is.valid

Validation Subroutine to Test the Bootstrap Set of Indices