FutRuleApp

<p>This function creates a web application with a Shiny-based graphical user interface to facilitate the process of defining an optimal futility stopping rule at an interim analysis in a Phase II or Phase III clinical trial. The application supports the same functionality as the <code>FutRule</code> function. For an example of the function call, see FutRuleExample1.</p>

Efficient simulation-based power and sample size calculations are supported for a
broad class of late-stage clinical trials. The following modules are included in
the package:
Adaptive designs with data-driven sample size or event count re-estimation,
Adaptive designs with data-driven treatment selection,
Adaptive designs with data-driven population selection,
Optimal selection of a futility stopping rule,
Event prediction in event-driven trials,
Adaptive trials with response-adaptive randomization (experimental module),
Traditional trials with multiple objectives (experimental module).
Traditional trials with cluster-randomized designs (experimental module).

Alex Dmitrienko

MedianaDesigner

FutRuleApp: Graphical user interface for an optimal selection of a futility stopping rule at an interim analysis

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See Also