mergeExprs: Merge gene expression data sets

Description

Merges gene expression data from different studies.

Usage

mergeExprs(...)

Arguments

...

Input objects can be any combination of mergeExpressionSet, ExpressionSet, matrix or a list. A list should have the following slots: expression matrix, pheno data matrix, gene names vector, notes. The order of the four slots is fixed. A matrix should have genes ids as its row names, as should the exprs slot of an ExpressionSet. Since merging depends on geneids, these conventions are essential.

Value

Details

The mergeExpressionSet object is the standard input for all functions in the MergeMaid package. Use the mergeExprs function when creating mergeExpressionSet objects to ensure that all necessary information is available for further analysis.

Examples

Run this code

  if(require(Biobase) & require(MASS)){
  data(mergeData)
  merged  <-mergeExprs(sample1,sample2,sample3)

  rr<-rnorm(200*22,0,1)
  mm<-matrix(rr,200,22)
  rownames(mm)<-sample2[[3]]
  merge.m<-mergeExprs(sample1,mm,sample2)
  intcor.m<-intCor(merge.m)
  plot(merge.m)

  rr<-rnorm(200*50,0,1)
  mm2<-matrix(rr,200,50)
  ph.ll<-as.data.frame(rbinom(50,1,.5))
  ll<-list(mm2,ph.ll,sample2[[3]],"list 2")
  merge.t<-mergeExprs(sample1,mm,sample2,ll)
  intcor.t<-intCor(merge.t)
  plot(merge.t)

  merge.a<-mergeExprs(sample3,merge.m,ll)
  inter<-intersection(merge.a)
  summary(merge.a)
  }