MetaSKAT (version 0.90)

Meta Analysis for SNP-Set (Sequence) Kernel Association Test

Description

Functions for Meta-analysis Burden Test, Sequence Kernel Association Test (SKAT) and Optimal SKAT (SKAT-O) by Lee et al. (2013) . These methods use summary-level score statistics to carry out gene-based meta-analysis for rare variants.

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Version

Install

install.packages('MetaSKAT')

Monthly Downloads

223

Version

0.90

License

GPL (>= 2)

Maintainer

Seunggeun Lee

Last Published

October 8th, 2024

Functions in MetaSKAT (0.90)

Meta_Null_Model

Get parameters and residuals from H0

Example

Example dataset

Open_MSSD_File_2Read

Read Meta SSD and Info files

MetaSKAT_MSSD_OneSet

Meta analysis SKAT with summary data from each study cohort.

Generate_Meta_Files

Generate summary statistics files

MetaSKAT_wZ

Meta analysis SKAT with individual level genotype data