miRNA_loadQualityThreshold

This function loads from file a data frame containing the quality threshold values for a set of miRNAs.

A complete and dedicated analytical toolbox for quality control and diagnosis based on subject-related measurements of micro-RNA (miRNA) expressions. The package consists of a set of functions that allow to train, optimize and use a Bayesian classifier that relies on multiplets of measured miRNA expressions. The package also implements the quality control tools required to preprocess input datasets. In addition, the package provides a function to carry out a statistical analysis of miRNA expressions, which can give insights to improve the classifier's performance. The method implemented in the package was first introduced in L. Ricci, V. Del Vescovo, C. Cantaloni, M. Grasso, M. Barbareschi and M. A. Denti, "Statistical analysis of a Bayesian classifier based on the expression of miRNAs", BMC Bioinformatics 16:287, 2015 <doi:10.1186/s12859-015-0715-9>. The package is thoroughly described in M. Castelluzzo, A. Perinelli, S. Detassis, M. A. Denti and L. Ricci, "MiRNA-QC-and-Diagnosis: An R package for diagnosis based on MiRNA expression", SoftwareX 12:100569, 2020 <doi:10.1016/j.softx.2020.100569>. Please cite both these works if you use the package for your analysis. DISCLAIMER: The software in this package is for general research purposes only and is thus provided WITHOUT ANY WARRANTY. It is NOT intended to form the basis of clinical decisions. Please refer to the GNU General Public License 3.0 (GPLv3) for further information.

Alessio Perinelli

MiRNAQCD

Micro-RNA Quality Control and Diagnosis

Michele Castelluzzo

Simone Detassis

Michela Alessandra Denti

Leonardo Ricci

miRNA_loadQualityThreshold function

<dl><dt>inputFileName</dt>
<dd>Name of the file to be loaded. The file has to contain at least the columns 'miRNA', 'QualityThreshold' (not necessarily in this order).</dd>
<dt>sep</dt>
<dd>Field separator character; the default is any white space (one or more spaces or tabulations).</dd></dl>

Arguments

Load quality threshold values. — miRNA_loadQualityThreshold

<dl>

<dt>inputFileName</dt>
<dd>Name of the file to be loaded. The file has to contain at least the columns 'miRNA', 'QualityThreshold' (not necessarily in this order).</dd>


<dt>sep</dt>
<dd>Field separator character; the default is any white space (one or more spaces or tabulations).</dd>

</dl>

miRNA_loadQualityThreshold: Load quality threshold values.

Description

Usage

Value

Arguments

Examples