miRNA_plotROC

Generates a plot of the ROC curve out of the input dataset.

A complete and dedicated analytical toolbox for quality control and diagnosis based on subject-related measurements of micro-RNA (miRNA) expressions. The package consists of a set of functions that allow to train, optimize and use a Bayesian classifier that relies on multiplets of measured miRNA expressions. The package also implements the quality control tools required to preprocess input datasets. In addition, the package provides a function to carry out a statistical analysis of miRNA expressions, which can give insights to improve the classifier's performance. The method implemented in the package was first introduced in L. Ricci, V. Del Vescovo, C. Cantaloni, M. Grasso, M. Barbareschi and M. A. Denti, "Statistical analysis of a Bayesian classifier based on the expression of miRNAs", BMC Bioinformatics 16:287, 2015 <doi:10.1186/s12859-015-0715-9>. The package is thoroughly described in M. Castelluzzo, A. Perinelli, S. Detassis, M. A. Denti and L. Ricci, "MiRNA-QC-and-Diagnosis: An R package for diagnosis based on MiRNA expression", SoftwareX 12:100569, 2020 <doi:10.1016/j.softx.2020.100569>. Please cite both these works if you use the package for your analysis. DISCLAIMER: The software in this package is for general research purposes only and is thus provided WITHOUT ANY WARRANTY. It is NOT intended to form the basis of clinical decisions. Please refer to the GNU General Public License 3.0 (GPLv3) for further information.

Alessio Perinelli

MiRNAQCD

Micro-RNA Quality Control and Diagnosis

Michele Castelluzzo

Simone Detassis

Michela Alessandra Denti

Leonardo Ricci

miRNA_plotROC function

<dl><dt>inputDataset</dt>
<dd>Dataset (data frame) to be used for the plot.</dd>
<dt>outputFileLabel</dt>
<dd>Label to be used to build the name of the output file.</dd>
<dt>plotFormat</dt>
<dd>String to set the format of the output file. Can either be 'pdf' (default) or 'png'.</dd></dl>

Arguments

Plot of classifier ROC curve. — miRNA_plotROC

<dl>

<dt>inputDataset</dt>
<dd>Dataset (data frame) to be used for the plot.</dd>


<dt>outputFileLabel</dt>
<dd>Label to be used to build the name of the output file.</dd>


<dt>plotFormat</dt>
<dd>String to set the format of the output file. Can either be 'pdf' (default) or 'png'.</dd>

</dl>

miRNA_plotROC: Plot of classifier ROC curve.

Description

Usage

Value

Arguments