PlotRunEnrichment

Plot running miRNAs enrichment score for the input pathway

The tools for 'MicroRNA Set Enrichment Analysis' can identify risk pathways(or prior gene sets) regulated by microRNA set in the context of microRNA expression data. (1) This package constructs a correlation profile of microRNA and pathways by the hypergeometric statistic test. The gene sets of pathways derived from the three public databases (Kyoto Encyclopedia of Genes and Genomes ('KEGG'); 'Reactome'; 'Biocarta') and the target gene sets of microRNA are provided by four databases('TarBaseV6.0'; 'mir2Disease'; 'miRecords'; 'miRTarBase';). (2) This package can quantify the change of correlation between microRNA for each pathway(or prior gene set) based on a microRNA expression data with cases and controls. (3) This package uses the weighted Kolmogorov-Smirnov statistic to calculate an enrichment score (ES) of a microRNA set that co-regulate to a pathway , which reflects the degree to which a given pathway is associated with the specific phenotype. (4) This package can provide the visualization of the results.

Junwei Han

MiRSEA

'MicroRNA' Set Enrichment Analysis

PlotRunEnrichment function

<dl><dt>miRlist</dt>
<dd>A list of miRNA LIST result obtained from the MsReport function</dd></dl>

Arguments

Junwei Han<a href="/link/hanjunwei1981%40163.com?package=MiRSEA&version=1.1.1" data-mini-rdoc="MiRSEA::hanjunwei1981@163.com">hanjunwei1981@163.com</a>,Siyao Liu <a href="/link/liusiyao29%40163.com?package=MiRSEA&version=1.1.1" data-mini-rdoc="MiRSEA::liusiyao29@163.com">liusiyao29@163.com</a>

Author

Plot running microRNAs(miRNAs) enrichment score — PlotRunEnrichment

<dl>

<dt>miRlist</dt>
<dd>A list of miRNA LIST result obtained from the MsReport function</dd>

</dl>

Junwei Han<a href='mailto:hanjunwei1981@163.com'>hanjunwei1981@163.com</a>,Siyao Liu <a href='mailto:liusiyao29@163.com'>liusiyao29@163.com</a>

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PlotRunEnrichment: Plot running microRNAs(miRNAs) enrichment score

Description

Usage

Arguments

Author

See Also

Examples