fun_load_genome

This function attempts to load the appropriate genome.

Clinical sequencing of tumor is usually performed on formalin-fixed
and paraffin-embedded samples and have many sequencing errors. We found that
the majority of these errors are detected in chimeric read caused by
single-strand DNA with micro-homology. Our filtering pipeline focuses on the
uneven distribution of the artifacts in each read and removes such errors in
formalin-fixed and paraffin-embedded samples without over-eliminating the
true mutations detected in fresh frozen samples.

Masachika Ikegami

MicroSEC

Sequence Error Filter for Formalin-Fixed and Paraffin-Embedded
Samples

fun_load_genome function

<dl><dt>organism</dt>
<dd>Human or Mouse genome.</dd></dl>

Arguments

Genome loading function. — fun_load_genome

<dl>

<dt>organism</dt>
<dd>Human or Mouse genome.</dd>

</dl>

fun_load_genome: Genome loading function.

Description

Usage

Value

Arguments

Examples