md_gr


Prior to inferring de novo trio copy number states, the log R
ratios are segmented independently for each individual in a
<code>ParentOffsping</code> class. The segmentation results are recorded
in separate <code>GRanges</code> objects for the parents. For
segmentation of the offspring log R ratios and the minimum
distance, the segments are stored in separate <code>GRangesList</code>
objects.  For convenience, these <code>GRanges</code>,
<code>GRangesList</code>, and pedigree information are bound in a single
container referred to as a <code>MinDistGRanges</code> object.  The
example <code>MinDistGRanges</code> object provided in this package was
obtained from the segmentation of the data stored in the example
<code>MinDistExperiment</code> object.


Analysis of de novo copy number variants in trios from
high-dimensional genotyping platforms.

Robert Scharpf

MinimumDistance

A Package for De Novo CNV Detection in Case-Parent Trios

md_gr function

Format

Prior to inferring de novo trio copy number states, the log R
ratios are segmented independently for each individual in a
<code>ParentOffsping</code> class. The segmentation results are recorded
in separate <code>GRanges</code> objects for the parents. For
segmentation of the offspring log R ratios and the minimum
distance, the segments are stored in separate <code>GRangesList</code>
objects.  For convenience, these <code>GRanges</code>,
<code>GRangesList</code>, and pedigree information are bound in a single
container referred to as a <code>MinDistGRanges</code> object.  The
example <code>MinDistGRanges</code> object provided in this package was
obtained from the segmentation of the data stored in the example
<code>MinDistExperiment</code> object.

md_gr: An example `MinDistGRanges` object

Description

Arguments

Format