NBBttest (version 1.0.1)

betaparametab: Estimation of parameters alpha (\(\alpha\)) and beta (\(\beta\)) of beta distribution

Description

Parameters alpha(a) and beta (b) in betat distribution are estimated by using an iteration algorithm.

Usage

betaparametab(xn, w, P, V)

Arguments

xn

column vector, a set of library sizes.

w

column vector, a set of weights.

P

proportion of counts of a gene or an isoform.

V

variance of proportions of counts of a gene or an isoform over m replicate libraries in a condition.

Value

return parameters a and b.

References

Baggerly KA, Deng L, Morris JS, Aldaz CM (2003) Differential expression in SAGE: accounting for normal between-library variation. Bioinformatics 19: 1477-1483.

See Also

betaparametVP, betaparametw

Examples

# NOT RUN {
XX<-c(2000,2000,2000)
p<-0.15
V=0.004
w<-c(0.3,0.3,0.3)
betaparametab(xn=XX,w=w,P=p,V=V)
# }