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NBDesign (version 2.0.0)

Design and Monitoring of Clinical Trials with Negative Binomial Endpoint

Description

Calculate various functions needed for design and monitoring clinical trials with negative binomial endpoint with variable follow-up. This version has a few changes compared to the previous version 1.0.0, including (1) correct a typo in Type 1 censoring, mtbnull=bnull and (2) restructure the code to account for shape parameter equal to zero, i.e. Poisson scenario.

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Version

Install

install.packages('NBDesign')

Monthly Downloads

184

Version

2.0.0

License

GPL (>= 2)

Maintainer

Xiaodong Luo

Last Published

September 10th, 2020

Functions in NBDesign (2.0.0)

negint2

A utility functon to calculate the mean exposure under different scenarios
NBDesign-package

NBDesign
ynegbinompowersim

Two-sample sample size calculation for negative binomial distribution with variable follow-up
ynegbinompower

Two-sample sample size calculation for negative binomial distribution with variable follow-up
ynegbinomsize

Two-sample sample size calculation for negative binomial distribution with variable follow-up