pmvnorm_

mvtnorm::pmvnorm, but returns 0 if any lower boundary is larger than
any upper boundary

Methods to calculate optimal design parameters
for one- and two-stage three-arm group-sequential gold-standard
non-inferiority trial designs
with or without binding or nonbinding futility boundaries,
as described in Meis et al. (2023) <doi:10.1002/sim.9630>.

Jan Meis

OptimalGoldstandardDesigns

Design Parameter Optimization for Gold-Standard Non-Inferiority
Trials

pmvnorm_ function

<dl><dt>upper</dt>
<dd>the vector of upper limits of length n.</dd>
<dt>lower</dt>
<dd>the vector of lower limits of length n.</dd>
<dt>...</dt>
<dd>additional parameters passed to <code><a href="/link/pmvnorm?package=OptimalGoldstandardDesigns&version=1.0.1" data-mini-rdoc="OptimalGoldstandardDesigns::pmvnorm">pmvnorm</a></code>.</dd></dl>

Arguments

mvtnorm::pmvnorm, but returns 0 if any lower boundary is larger than
any upper boundary — pmvnorm_

<dl>

<dt>upper</dt>
<dd>the vector of upper limits of length n.</dd>


<dt>lower</dt>
<dd>the vector of lower limits of length n.</dd>


<dt>...</dt>
<dd>additional parameters passed to <code><a href='https://rdrr.io/pkg/mvtnorm/man/pmvnorm.html'>pmvnorm</a></code>.</dd>

</dl>

pmvnorm_: mvtnorm::pmvnorm, but returns 0 if any lower boundary is larger than any upper boundary

Description

Usage

Value

Arguments

See Also