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OptimalTiming (version 0.1.0)

Optimal Timing Identification

Description

Identify the optimal timing for new treatment initiation during multiple state disease transition, including multistate model fitting, simulation of mean residual lifetime for a given transition state, and estimation of confidence interval. The method is referred to de Wreede, L., Fiocco, M., & Putter, H. (2011) .

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Version

Install

install.packages('OptimalTiming')

Monthly Downloads

143

Version

0.1.0

License

GPL (>= 2)

Maintainer

Xiao Lin

Last Published

November 14th, 2017

Functions in OptimalTiming (0.1.0)

SimCml

Simulated data for CML patients
sim.MTL

Simulate mean total lifetime
sim.los

internal
conf.MTL

Confidence interval of mean total lifetime
optim.fit

Fit multi-state model for optimization