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PADOG (version 1.14.0)

Pathway Analysis with Down-weighting of Overlapping Genes (PADOG)

Description

This package implements a general purpose gene set analysis method called PADOG that downplays the importance of genes that apear often accross the sets of genes to be analyzed. The package provides also a benchmark for gene set analysis methods in terms of sensitivity and ranking using 24 public datasets from KEGGdzPathwaysGEO package.

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Version

Version

1.14.0

License

GPL (>= 2)

Maintainer

Adi Laurentiu Tarca

Last Published

February 15th, 2017

Functions in PADOG (1.14.0)

compPADOG

Benchmark for gene set analysis methods using 24 datasets
filteranot

Remove duplicate probesets/probes from an gene expression matrix based on p-values from a moderated t-test, in order to apply a gene set analysis.
padog

Pathway Analysis with Down-weighting of Overlapping Genes (PADOG)