EvaluateModelInfusion

Evaluate an analytic model in infusion.

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Hervé Le Nagard

Jérémy Seurat

Tran Bach Nguyen

Caroline Bazzoli

Emmanuelle Comets

Anne Dubois

Cyrielle Dumont

Giulia Lestini

Thi Huyen Tram Nguyen

Thu Thuy Nguyen

Sylvie Retout

EvaluateModelInfusion function

<dl><dt>object</dt>
<dd>A <code>ModelInfusionEquations</code> object.</dd>
<dt>samplingTimesModel</dt>
<dd>A vector giving the sampling times of the model</dd>
<dt>inputsModel</dt>
<dd>A list containing the inputs used for the model evaluation.</dd>
<dt>computeFIM</dt>
<dd>A boolean if the FIM is computed or not.</dd></dl>

Arguments

Evaluate an analytic model in infusion. — EvaluateModelInfusion

<dl>

<dt>object</dt>
<dd>A <code>ModelInfusionEquations</code> object.</dd>


<dt>samplingTimesModel</dt>
<dd>A vector giving the sampling times of the model</dd>


<dt>inputsModel</dt>
<dd>A list containing the inputs used for the model evaluation.</dd>


<dt>computeFIM</dt>
<dd>A boolean if the FIM is computed or not.</dd>

</dl>

Evaluate an analytic model in infusion.

EvaluateModelInfusion: Evaluate an analytic model in infusion.

Description

Usage

Value

Arguments