FedorovWynnAlgorithm-class

FedorovWynnAlgorithm

Class <code>FedorovWynnAlgorithm</code> represents an initial variable for ODE model.

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Hervé Le Nagard

Jérémy Seurat

Tran Bach Nguyen

Caroline Bazzoli

Emmanuelle Comets

Anne Dubois

Cyrielle Dumont

Giulia Lestini

Thi Huyen Tram Nguyen

Thu Thuy Nguyen

Sylvie Retout

FedorovWynnAlgorithm-class function

Objects form the class <code>FedorovWynnAlgorithm</code> can be created by calls of the form <code>FedorovWynnAlgorithm(...)</code>
where (...) are the parameters for the <code>FedorovWynnAlgorithm</code> objects.

Objects from the class <code>FedorovWynnAlgorithm</code>

<dl>
<dt><code>initialElementaryProtocols</code>:</dt>
<dd>A list of vector for the intial elementary protocols.</dd></dl><dt><code>numberOfSubjects</code>:</dt>
<dd>A vector for the number of subjects.</dd><dt><code>proportionsOfSubjects</code>:</dt>
<dd>A vector for the number of subjects.</dd><dt><code>OptimalDesign</code>:</dt>
<dd>A object Design giving the optimal Design.</dd><dt><code>showProcess</code>:</dt>
<dd>A boolean to show the process or not.</dd><dt><code>FisherMatrix</code>:</dt>
<dd>A vector giving the Fisher Information</dd><dt><code>optimalFrequencies</code>:</dt>
<dd>A vector of the optimal frequencies.</dd><dt><code>optimalSamplingTimes</code>:</dt>
<dd>A list of vectors for the optimal sampling times.</dd><dt><code>optimalDoses</code>:</dt>
<dd>A vector for the optimal doses.</dd>

Slots for <code>FedorovWynnAlgorithm</code> objects

Class "FedorovWynnAlgorithm" — FedorovWynnAlgorithm-class

Objects form the class <code>FedorovWynnAlgorithm</code> can be created by calls of the form <code>FedorovWynnAlgorithm(...)</code>
where (...) are the parameters for the <code>FedorovWynnAlgorithm</code> objects.

<dl>
<dt><code>initialElementaryProtocols</code>:</dt>
<dd>A list of vector for the intial elementary protocols.</dd>

<dt><code>numberOfSubjects</code>:</dt>
<dd>A vector for the number of subjects.</dd>

<dt><code>proportionsOfSubjects</code>:</dt>
<dd>A vector for the number of subjects.</dd>

<dt><code>OptimalDesign</code>:</dt>
<dd>A object Design giving the optimal Design.</dd>

<dt><code>showProcess</code>:</dt>
<dd>A boolean to show the process or not.</dd>

<dt><code>FisherMatrix</code>:</dt>
<dd>A vector giving the Fisher Information</dd>

<dt><code>optimalFrequencies</code>:</dt>
<dd>A vector of the optimal frequencies.</dd>

<dt><code>optimalSamplingTimes</code>:</dt>
<dd>A list of vectors for the optimal sampling times.</dd>

<dt><code>optimalDoses</code>:</dt>
<dd>A vector for the optimal doses.</dd>


</dl>

FedorovWynnAlgorithm-class: Class "FedorovWynnAlgorithm"

Description

Arguments

Objects from the class <code>FedorovWynnAlgorithm</code>

Slots for <code>FedorovWynnAlgorithm</code> objects