LibraryOfModels
is an S4 class that implements the library of models, consisting
of two libraries of PK and PD models respectively.
The PK library includes model with different administration routes (bolus, infusion, first-order absorption),
different number of compartments (from 1 to 3), and different types of eliminations (linear or Michaelis-Menten).
The PD model library, contains direct immediate models (e.g. Emax and Imax) with various baseline models,
and turnover response models. The PK/PD models, on the other hand, are obtained with combination of the models
from the PK and PD model libraries. Throught the use of the LibraryOfModels
PFIM handles both analytical and ODE models and offers the possibility to the user to define his own models.
The library of pharmacokinetic (PK) and pharmacodynamic (PD) models is described in the vignette LibraryOfModels.
LibraryOfModels
objects are created by calls to LibraryOfModels
and contain the following slots:
nameLibraryOfModels
:A character string giving the name of the library of models.
contentsLibraryOfModels
:A list of the PK, PD and PKPD models that are in the library of models.