ModelParameter-class

ModelParameter

Class <code>ModelParameter</code> represents a parameters theta
included in f(x,theta)
theta = mu, covariance_matrix
mu - parameter that acts in the individual model
covariance_matrix - additional parameter for the population model
theta_distribution - Distribution.

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Hervé Le Nagard

Jérémy Seurat

Tran Bach Nguyen

Caroline Bazzoli

Emmanuelle Comets

Anne Dubois

Cyrielle Dumont

Giulia Lestini

Thi Huyen Tram Nguyen

Thu Thuy Nguyen

Sylvie Retout

ModelParameter-class function

Objects form the class <code>ModelParameter</code> can be created by calls of the form <code>ModelParameter(...)</code> where
(...) are the parameters for the <code>ModelParameter</code> objects.

Objects from the class

<dl>
<dt><code>name</code>:</dt>
<dd>A character string giving the name of the parameter.</dd></dl><dt><code>mu</code>:</dt>
<dd>A numeric giving the value of the mean mu.</dd><dt><code>omega</code>:</dt>
<dd>A numeric giving the value of the variance.</dd><dt><code>distribution</code>:</dt>
<dd>An object of the class <code>Distribution</code>.</dd><dt><code>fixed</code>:</dt>
<dd>A boolean giving if the parameter is fixed or remain to be estimated.</dd><dt><code>fixedMu</code>:</dt>
<dd>A boolean giving if the mean mu is fixed or remain to be estimaed.</dd>

Slots for ModelParameter objects

Class "ModelParameter" — ModelParameter-class

Objects form the class <code>ModelParameter</code> can be created by calls of the form <code>ModelParameter(...)</code> where
(...) are the parameters for the <code>ModelParameter</code> objects.

<dl>
<dt><code>name</code>:</dt>
<dd>A character string giving the name of the parameter.</dd>

<dt><code>mu</code>:</dt>
<dd>A numeric giving the value of the mean mu.</dd>

<dt><code>omega</code>:</dt>
<dd>A numeric giving the value of the variance.</dd>

<dt><code>distribution</code>:</dt>
<dd>An object of the class <code>Distribution</code>.</dd>

<dt><code>fixed</code>:</dt>
<dd>A boolean giving if the parameter is fixed or remain to be estimated.</dd>

<dt><code>fixedMu</code>:</dt>
<dd>A boolean giving if the mean mu is fixed or remain to be estimaed.</dd>


</dl>

ModelParameter-class: Class "ModelParameter"

Description

Arguments

Objects from the class

Slots for ModelParameter objects