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PFIM (version 5.0)

Optimize: Set the optimization process.

Description

Set the optimization process.

Optimization with the Fedorov-Wynn algorithm.

Optimization with the Multiplicative Algorithm.

Optimization with the PGBO Algorithm.

Design optimization withe the Simplex algorithm.

Usage

Optimize(
  object,
  pfimProject,
  designs,
  statistical_model,
  cond_init,
  constraint,
  typeFim
)

# S4 method for FedorovWynnAlgorithm Optimize(object, statistical_model, cond_init, constraint, typeFim)

# S4 method for MultiplicativeAlgorithm Optimize(object, statistical_model, cond_init, constraint, typeFim)

# S4 method for PGBOAlgorithm Optimize(object, pfimProject, designs, statistical_model, constraint, typeFim)

# S4 method for SimplexAlgorithm Optimize(object, designs, statistical_model, constraint, typeFim)

Value

A design object giving the optimal design.

The FedorovWynnAlgorithm object with:

  • {OptimalDesign}:The optimal Design.

  • {optimalDoses}:A vector giving the optimal doses.

  • {FisherMatrix}:A matrix giving The Fisher Information Matrix.

  • {optimalFrequencies}:A vector of the optimal frequencies.

  • {optimalSamplingTimes}:A list of vectors of the optimal sampling times.

The MultiplicativeAlgorithm object with:

  • {OptimalDesign}:A Design object giving the optimal design.

  • {FinalWeights}:A list of the optimal weights.

  • {iteration_final }:A numeric of the final iteration of the process.

  • {allArms}:A list of all the arms in the optimal design.

The PGBOAlgorithm object with:

  • {resultsOptimization}:A dataframe giving the results for each iteration.

  • {OptimalDesign}:A Design object giving the optimal design.

  • {iteration_fin }:A numeric of the final iteration of the process.

A Design object giving the optimal design.

Arguments

object

An Optimize object.

pfimProject

A PFIMProject object.

designs

A Design object.

statistical_model

A StatisticalModel object.

cond_init

: A list of numeric giving the values of the initial conditions.

constraint

A Constraint object.

typeFim

A FIM object.