SamplingConstraint-class

SamplingConstraint

Class "SamplingConstraint" storing information concerning sampling constraint.

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Hervé Le Nagard

Jérémy Seurat

Tran Bach Nguyen

Caroline Bazzoli

Emmanuelle Comets

Anne Dubois

Cyrielle Dumont

Giulia Lestini

Thi Huyen Tram Nguyen

Thu Thuy Nguyen

Sylvie Retout

SamplingConstraint-class function

<code>SamplingConstraint</code> objects are typically created by calls to <code>SamplingConstraint</code> and contain the following slots:

Objects from the class

<dl>
<dt><code>response</code>:</dt>
<dd>A character string for the name of the response of the model.</dd></dl><dt><code>numberOptimisability</code>:</dt>
<dd>A boolean that gives TRUE for optimizing the number of times and FALSE for fixing the number of times.</dd><dt><code>numberOfSamplingTimes</code>:</dt>
<dd>A vector of the number of sampling times.</dd><dt><code>fixedTimes</code>:</dt>
<dd>A vector of the number of fixed times.</dd><dt><code>continuousSamplingTimes</code>:</dt>
<dd>A list of the continuous sampling times.</dd><dt><code>discretSamplingTimes</code>:</dt>
<dd>A list of the discrete sampling times.</dd><dt><code>min_delay</code>:</dt>
<dd>A numeric giving the minimal interval in the sampling times.</dd>

Slots for <code>SamplingConstraint</code> objects

Class "SamplingConstraint" — SamplingConstraint-class

<dl>
<dt><code>response</code>:</dt>
<dd>A character string for the name of the response of the model.</dd>

<dt><code>numberOptimisability</code>:</dt>
<dd>A boolean that gives TRUE for optimizing the number of times and FALSE for fixing the number of times.</dd>

<dt><code>numberOfSamplingTimes</code>:</dt>
<dd>A vector of the number of sampling times.</dd>

<dt><code>fixedTimes</code>:</dt>
<dd>A vector of the number of fixed times.</dd>

<dt><code>continuousSamplingTimes</code>:</dt>
<dd>A list of the continuous sampling times.</dd>

<dt><code>discretSamplingTimes</code>:</dt>
<dd>A list of the discrete sampling times.</dd>

<dt><code>min_delay</code>:</dt>
<dd>A numeric giving the minimal interval in the sampling times.</dd>


</dl>

Class "SamplingConstraint"

SamplingConstraint-class: Class "SamplingConstraint"

Description

Arguments

Objects from the class

Slots for <code>SamplingConstraint</code> objects