modifySamplingTimes

Modify the sampling times of an arm.

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Hervé Le Nagard

Jérémy Seurat

Tran Bach Nguyen

Caroline Bazzoli

Emmanuelle Comets

Anne Dubois

Cyrielle Dumont

Giulia Lestini

Thi Huyen Tram Nguyen

Thu Thuy Nguyen

Sylvie Retout

modifySamplingTimes function

<dl><dt>object</dt>
<dd>An object <code>Arm</code> from the class Arm.</dd>
<dt>outcome</dt>
<dd>A character string giving the name of the outcome ie the name of the response.</dd>
<dt>samplingTimes</dt>
<dd>A vector of numeric giving the new sampling times.</dd></dl>

Arguments

Modify the sampling times of an arm. — modifySamplingTimes

<dl>

<dt>object</dt>
<dd>An object <code>Arm</code> from the class Arm.</dd>


<dt>outcome</dt>
<dd>A character string giving the name of the outcome ie the name of the response.</dd>


<dt>samplingTimes</dt>
<dd>A vector of numeric giving the new sampling times.</dd>

</dl>

Modify the sampling times of an arm.

modifySamplingTimes: Modify the sampling times of an arm.

Description

Usage

Value

Arguments