AdministrationConstraints-class

AdministrationConstraints

The class <code>AdministrationConstraints</code> represents the constraint of an input to the system.
The class stores information concerning the constraints for the dosage regimen:
response of the model, amount of dose.

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Jérémy Seurat

Lucie Fayette

Emmanuelle Comets

Sylvie Retout

AdministrationConstraints-class function

Objects form the class <code>AdministrationConstraints</code> can be created by calls of the form <code>AdministrationConstraints(...)</code> where
(...) are the parameters for the <code>AdministrationConstraints</code> objects.

Objects from the class

<dl>
 <dt><code>outcome</code>:</dt>
<dd>A character string giving the name for the response of the model.</dd> <dt><code>doses</code>:</dt>
<dd>A numeric vector giving the amount of doses.</dd> 
</dl>

Slots for <code>AdministrationConstraints</code> objects

Class "AdministrationConstraints" — AdministrationConstraints-class

Objects form the class <code>AdministrationConstraints</code> can be created by calls of the form <code>AdministrationConstraints(...)</code> where
(...) are the parameters for the <code>AdministrationConstraints</code> objects.

<dl>
 <dt><code>outcome</code>:</dt>
<dd>A character string giving the name for the response of the model.</dd>

 <dt><code>doses</code>:</dt>
<dd>A numeric vector giving the amount of doses.</dd>

 
</dl>

AdministrationConstraints-class: Class "AdministrationConstraints"

Description

Arguments

Objects from the class

Slots for <code>AdministrationConstraints</code> objects