checkSamplingTimeConstraintsForContinuousOptimization

checkSamplingTimeConstraintsForContinuousOptimization,SamplingTimeConstraints-method

Check for the samplingTime constraints for continuous optimization

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Jérémy Seurat

Lucie Fayette

Emmanuelle Comets

Sylvie Retout

checkSamplingTimeConstraintsForContinuousOptimization function

<dl><dt>object</dt>
<dd>An object from the class SamplingTimeConstraints.</dd>
<dt>arm</dt>
<dd>An object from the class Arm.</dd>
<dt>newSamplings</dt>
<dd>A vector giving the new sampling.</dd>
<dt>outcome</dt>
<dd>The outcomes for the model.</dd></dl>

Arguments

Check for the samplingTime constraints for continuous optimization — checkSamplingTimeConstraintsForContinuousOptimization

<dl>

<dt>object</dt>
<dd>An object from the class SamplingTimeConstraints.</dd>


<dt>arm</dt>
<dd>An object from the class Arm.</dd>


<dt>newSamplings</dt>
<dd>A vector giving the new sampling.</dd>


<dt>outcome</dt>
<dd>The outcomes for the model.</dd>

</dl>

checkSamplingTimeConstraintsForContinuousOptimization: Check for the samplingTime constraints for continuous optimization

Description

Usage

Value

Arguments