generateFimsFromConstraints

generateFimsFromConstraints,Optimization-method

Generate the fim from the constraints

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Jérémy Seurat

Lucie Fayette

Emmanuelle Comets

Sylvie Retout

generateFimsFromConstraints function

<dl><dt>object</dt>
<dd>An object from the class Optimization.</dd>
<dt>fims</dt>
<dd>A list of object from the class Fim.</dd></dl>

Arguments

Generate the fim from the constraints — generateFimsFromConstraints

<dl>

<dt>object</dt>
<dd>An object from the class Optimization.</dd>


<dt>fims</dt>
<dd>A list of object from the class Fim.</dd>

</dl>

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generateFimsFromConstraints: Generate the fim from the constraints

Description

Usage

Value

Arguments