getConditionNumberVarianceEffects

Get the condition number of the matrix of the variance effects.

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Jérémy Seurat

Lucie Fayette

Emmanuelle Comets

Sylvie Retout

getConditionNumberVarianceEffects function

<dl><dt>object</dt>
<dd>An object from the class Fim..</dd></dl>

Arguments

Get the condition number of the matrix of the variance effects. — getConditionNumberVarianceEffects

<dl>

<dt>object</dt>
<dd>An object from the class Fim..</dd>

</dl>

getConditionNumberVarianceEffects: Get the condition number of the matrix of the variance effects.

Description

Usage

Value

Arguments