getSamplingTimeConstraint

Get the sampling times constraints by outcome.

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Jérémy Seurat

Lucie Fayette

Emmanuelle Comets

Sylvie Retout

getSamplingTimeConstraint function

<dl><dt>object</dt>
<dd>An object <code>Arm</code> from the class Arm.</dd>
<dt>outcome</dt>
<dd>A string giving the name of the outcome.</dd></dl>

Arguments

Get the sampling times constraints by outcome. — getSamplingTimeConstraint

<dl>

<dt>object</dt>
<dd>An object <code>Arm</code> from the class Arm.</dd>


<dt>outcome</dt>
<dd>A string giving the name of the outcome.</dd>

</dl>

getSamplingTimeConstraint: Get the sampling times constraints by outcome.

Description

Usage

Value

Arguments