setSamplingTimesConstraints

Set the sampling times constraints.

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Jérémy Seurat

Lucie Fayette

Emmanuelle Comets

Sylvie Retout

setSamplingTimesConstraints function

<dl><dt>object</dt>
<dd>An object <code>Arm</code> from the class Arm.</dd>
<dt>samplingTimesConstraints</dt>
<dd>An object <code>SamplingTimeConstraints</code> from the class SamplingTimeConstraints.</dd></dl>

Arguments

Set the sampling times constraints. — setSamplingTimesConstraints

<dl>

<dt>object</dt>
<dd>An object <code>Arm</code> from the class Arm.</dd>


<dt>samplingTimesConstraints</dt>
<dd>An object <code>SamplingTimeConstraints</code> from the class SamplingTimeConstraints.</dd>

</dl>

setSamplingTimesConstraints: Set the sampling times constraints.

Description

Usage

Value

Arguments