setTimeDose

Set the times vector when doses are given.

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Jérémy Seurat

Lucie Fayette

Emmanuelle Comets

Sylvie Retout

setTimeDose function

<dl><dt>object</dt>
<dd>An object <code>Administration</code> from the class Administration.</dd>
<dt>timeDose</dt>
<dd>A numeric value of the time dose.</dd></dl>

Arguments

Set the times vector when doses are given. — setTimeDose

<dl>

<dt>object</dt>
<dd>An object <code>Administration</code> from the class Administration.</dd>


<dt>timeDose</dt>
<dd>A numeric value of the time dose.</dd>

</dl>

setTimeDose: Set the times vector when doses are given.

Description

Usage

Value

Arguments