getSamplingTimesConstraints

getSamplingTimesConstraints,Arm-method

Get the sampling times constraints.

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Jérémy Seurat

Lucie Fayette

getSamplingTimesConstraints function

<dl><dt>object</dt>
<dd>An object <code>Arm</code> from the class Arm.</dd></dl>

Arguments

getSamplingTimesConstraints — getSamplingTimesConstraints

<dl>

<dt>object</dt>
<dd>An object <code>Arm</code> from the class Arm.</dd>

</dl>

getSamplingTimesConstraints: getSamplingTimesConstraints

Description

Usage

Value

Arguments