setSamplingTimesConstraints

setSamplingTimesConstraints,Arm-method

Set the sampling times constraints.

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Jérémy Seurat

Lucie Fayette

setSamplingTimesConstraints function

<dl><dt>object</dt>
<dd>An object <code>Arm</code> from the class Arm.</dd>
<dt>samplingTimesConstraints</dt>
<dd>An object <code>SamplingTimeConstraints</code> from the class SamplingTimeConstraints.</dd></dl>

Arguments

setSamplingTimesConstraints — setSamplingTimesConstraints

<dl>

<dt>object</dt>
<dd>An object <code>Arm</code> from the class Arm.</dd>


<dt>samplingTimesConstraints</dt>
<dd>An object <code>SamplingTimeConstraints</code> from the class SamplingTimeConstraints.</dd>

</dl>

setSamplingTimesConstraints: setSamplingTimesConstraints

Description

Usage

Value

Arguments