AdministrationConstraints

The class <code>AdministrationConstraints</code> represents the constraint of an input to the system.
The class stores information concerning the constraints for the dosage regimen.

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Jérémy Seurat

AdministrationConstraints function

<dl><dt>outcome</dt>
<dd>A string giving the outcome for the administration.</dd>
<dt>doses</dt>
<dd>A vector of double giving the doses.</dd></dl>

Arguments

AdministrationConstraints — AdministrationConstraints

<dl>

<dt>outcome</dt>
<dd>A string giving the outcome for the administration.</dd>


<dt>doses</dt>
<dd>A vector of double giving the doses.</dd>

</dl>

AdministrationConstraints: AdministrationConstraints

Description

Usage

Arguments